LL-37

Research Guide · Laboratory Use Only

Antimicrobial peptide

LL-37 is the only human cathelicidin antimicrobial peptide, a key effector of the innate immune system.

What it is

LL-37 is studied for directly disrupting microbial membranes and for immunomodulatory signaling — influencing chemotaxis, wound-healing pathways, and inflammation. It is a central reference peptide in antimicrobial-peptide research.

How it’s studied

Research interest covers antimicrobial activity, innate-immune signaling, and tissue-repair models.

Research focus areas

  • Membrane-disrupting antimicrobial activity
  • Innate-immune and chemotaxis signaling
  • Wound-healing pathway research
  • Host-defense peptide biology

Handling & documentation

In the laboratory this material is typically supplied as a lyophilized (freeze-dried) powder and reconstituted with bacteriostatic or sterile water for in-vitro work. As with any research compound, the quality signal that matters most is a lot-specific Certificate of Analysis (COA) from an independent lab, confirming identity by mass spectrometry and purity by HPLC. Store per the supplier’s guidance and verify the COA before use.

Browse the COA-verified research catalog →

For laboratory research use only. This content is educational and written for a research context. The compound is a research-use-only (RUO) material — not a drug, supplement, food, or cosmetic, not for human or veterinary use, and no claims are made to diagnose, treat, cure, or prevent any condition. No dosing or protocols are provided.

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