Melanotan II

Research Guide · Laboratory Use Only

Melanocortin agonist

Melanotan II is a synthetic analog of α-MSH and a broad melanocortin-receptor agonist, studied mainly for pigmentation biology.

What it is

Melanotan II activates several melanocortin receptors, including MC1R (linked to melanin synthesis) and MC4R. Its research profile spans pigmentation pathways and, through MC4R, appetite and behavioral signaling.

How it’s studied

Research focuses on melanocortin-receptor biology and melanin-synthesis pathways.

Research focus areas

  • MC1R signaling and melanin synthesis
  • Broad melanocortin-receptor activation
  • Pigmentation-pathway research
  • MC4R-linked appetite signaling

Handling & documentation

In the laboratory this material is typically supplied as a lyophilized (freeze-dried) powder and reconstituted with bacteriostatic or sterile water for in-vitro work. As with any research compound, the quality signal that matters most is a lot-specific Certificate of Analysis (COA) from an independent lab, confirming identity by mass spectrometry and purity by HPLC. Store per the supplier’s guidance and verify the COA before use.

Browse the COA-verified research catalog →

For laboratory research use only. This content is educational and written for a research context. The compound is a research-use-only (RUO) material — not a drug, supplement, food, or cosmetic, not for human or veterinary use, and no claims are made to diagnose, treat, cure, or prevent any condition. No dosing or protocols are provided.

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