ARA-290 (Cibinetide)

Research Guide · Laboratory Use Only

Tissue-protective peptide

ARA-290 (cibinetide) is a short peptide derived from the tissue-protective region of erythropoietin (EPO), designed to separate EPO’s protective signaling from its blood-cell effects.

What it is

ARA-290 targets the innate repair receptor (IRR) rather than the classical EPO receptor, and is studied for tissue-protective and anti-inflammatory signaling without stimulating red-blood-cell production.

How it’s studied

Its research profile centers on neuropathic and tissue-protection models, including small-nerve-fiber research.

Research focus areas

  • Innate repair receptor (IRR) signaling
  • Neuropathy and small-fiber research models
  • Tissue protection separated from erythropoiesis
  • Anti-inflammatory signaling

Handling & documentation

In the laboratory this material is typically supplied as a lyophilized (freeze-dried) powder and reconstituted with bacteriostatic or sterile water for in-vitro work. As with any research compound, the quality signal that matters most is a lot-specific Certificate of Analysis (COA) from an independent lab, confirming identity by mass spectrometry and purity by HPLC. Store per the supplier’s guidance and verify the COA before use.

Browse the COA-verified research catalog →

For laboratory research use only. This content is educational and written for a research context. The compound is a research-use-only (RUO) material — not a drug, supplement, food, or cosmetic, not for human or veterinary use, and no claims are made to diagnose, treat, cure, or prevent any condition. No dosing or protocols are provided.

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