KPV

Research Guide · Laboratory Use Only

Anti-inflammatory tripeptide

KPV is a tripeptide (lysine-proline-valine) corresponding to the C-terminal fragment of α-melanocyte-stimulating hormone (α-MSH), studied for anti-inflammatory activity.

What it is

KPV is studied for entering cells and reducing pro-inflammatory signaling (including NF-κB-linked pathways), reproducing much of α-MSH’s anti-inflammatory effect without its pigmentation activity.

How it’s studied

Research interest centers on inflammation models, including gut and mucosal-inflammation research.

Research focus areas

  • Anti-inflammatory signaling (NF-κB pathway)
  • Gut and mucosal inflammation models
  • α-MSH fragment biology
  • Cellular inflammation research

Handling & documentation

In the laboratory this material is typically supplied as a lyophilized (freeze-dried) powder and reconstituted with bacteriostatic or sterile water for in-vitro work. As with any research compound, the quality signal that matters most is a lot-specific Certificate of Analysis (COA) from an independent lab, confirming identity by mass spectrometry and purity by HPLC. Store per the supplier’s guidance and verify the COA before use.

Browse the COA-verified research catalog →

For laboratory research use only. This content is educational and written for a research context. The compound is a research-use-only (RUO) material — not a drug, supplement, food, or cosmetic, not for human or veterinary use, and no claims are made to diagnose, treat, cure, or prevent any condition. No dosing or protocols are provided.

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